Sutherland Tanqua succulent route will take you through 4 main vegetation types, namely: Western Mountain Karoo, Mountain Renosterveld, Upland Succulent Karoo and Lowland Succulent Karoo.

Flora of the Succulent Karoo vegetation in Tanqua Karoo exhibit a clear north-south distribution, linking the flora of Namaqualand and Richtersveld with those of the Little Karoo. The Tanqua Karoo basin is thus an important dispersal route for plant taxa endemic to the Succulent Karoo vegetation.

The following are endemic species to be found in the Tanqua basin; Braunsia stayneri, Conophytum bicarinatum, Lithops comptonii, Hammeria salteri, etc.

The Roggeveld plateaux, in contrast, rather seem to have been supporting a "montane" flora, very similar to those which still occurs on the Drakensberg escarpment.

Unfortunately very little is known about the endemic "Rog of the Roggeveld", the Wild Rye grass (Secale africanum). This highly palatable species is nowadays restricted to a single site at Voëlfontein, but was previously probably abundant in this area.

The following are endemic species to be found on the Roggeveld plateaux; Babiana virginea, Daubenia aurea, Cliffortia arborea(Sterboom), Zaluzianskya sutherlandica, etc